How is primary epilepsy inherited?

Nobody knows precisely but the few genes identified thus far are not the cause of epilepsy in all breeds and, unfortunately, are not apparently involved in Australian Shepherd epilepsy. The only thing that is clear is that the inheritance is complex: It may involve multiple genes, gene regulation (things that turn genes on/off or up/down), or genes that confer risk factors. It is possible that environment may play some role – it clearly sometimes provides a trigger for seizures – but the roots of the disease are genetic.

Posted in: How do I handle epilepsy in my breeding program?