Sterile granuloma, sometimes called sterile pyogranuloma or either name preceded by “idiopathic”, is an immune mediated disease that cause masses or nodular skin lesions, usually on the face though they can occur anywhere. These lesions do not itch or cause pain.
Sterile granuloma is frequently mistaken for other skin conditions, including infections, foreign body reactions, and cancer. Diagnosis requires biopsy, culture, and sometimes bloodwork. Prognosis is good but the disease requires life-long treatment with steroids or other drugs.
Sterile granuloma is an immune mediated disease and may be autoimmune disease. Affected dogs should not be bred.